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1) A chronic disease that occurs when a person loses all athletic ability and in turn becomes a total doofus during any sporting event. Usually cured withing a short period of time, but may linger for years in some cases.

2) The inability to play any sort of sport, it is very contagious...as a matter of fact it sucks the atheletic ability out of anyone near a person that is infected with Kyleitis
Well Bryce didn't get the golf ball past the ladies' tees on his drives, looks like he has a case of acute Kyleitis.
by Schmegma June 22, 2006
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