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5. Knuckle up
To masturbate
The act of masturbation
Guy 1: Did you see Stacey?

Guy 2: Yeah, total nipple slip! I'm totally going to knuckle up to that later
1. Knuckle Up
July 9, 2006 Urban Word of the Day
To prepare to kick another's ass, getting prepared to engage in fisticuffs
If you get up in my grille, you best knuckle up, motherfucker
by stefanali pops Sep 13, 2005 add a video
2. knuckle up
a phrase uttered in encouragement meaning: "muster your courage, intestinal fortitude and love for the American-way in preparation for an upcoming (or admist a) challenge
of epic proportions!"
(uttered many times by one of the dudes in the movie "The Matrixs:Revolutions" during battle
against the electro-mechanical foe)
"Here they come boys ... Knuckle up!"
by abc Jul 13, 2004 add a video
3. knuckle up
to prepare to fight.
Guy 1 "i was at the bar chillin talkin to this girl after the band played, then this dude looked at me like he wanted a problem."

Guy 2 "what happened?"

Guy 1 "I had to knuckle up then his boy pulled him back."
4. knuckle up
TO Put Up YOUR Setz And get ready to fight
Knuckle up nucker
by shane Jun 18, 2003 add a video
6. Knuckle Up
The Act Of Whupping Someone's Ass!
BITCH All In My FACE We Bout 2 KNUCKLE UP In Did Bitch!!!
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