Reyes' other film credits include Martin Scorsese's Bringing Out the Dead, and the independent film Went to Coney Island on a Mission from God, Be Back by Five.
She can also be seen in the film Washington Heights. Additionally Reyes acted in and co-produced (with her husband) Taino, a short film which was screened at the 1999 New York International Latino Film Festival and at the 2001 Los Angeles Latino Film Festival. She has also made an appearance in the TV show Castle.
Reyes' television credits include 100 Centre Street and a guest stint on Third Watch. Her made-for-television movies include John Sanford's Mind Prey, with Eriq La Salle, The Prosecutors, the role of Luz Cuevas in the LMN biopic drama Little Girl Lost: The Delimar Vera Story, and a homeless woman in the 2006 Hallmark Channel movie, Our House.
Reyes has five sisters including a twin sister named Joselin who played a paramedic on Law & Order: Special Victims Unit. She is the cousin of Pop, R&B singer, model and actor Viancey.
She attended Hunter College in Manhattan, where her acting career started out. She was married to writer/director Edwin M. Figueroa for 11 years before they divorced.
Reyes and her boyfriend George Valencia have a daughter, Leila Rey, born on November 27, 2009.