Top Definition
A serious affliction that seems to affect celebrities only. When a formerly paparazzi-friendly celebrity stops talking to the cameras after entering a serious relationship. Named after John Mayer, who was glacial towards paparazzi during his relationship with Jennifer Aniston. Originally coined by Harvey Levin of TMZ.
After British lothario Russell Brand said he was "in love" with Katy Perry, he stopped talking to paparazzi. She gave him John Mayer Syndrome.
by geeksmakethebestlovers October 28, 2009

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