Someone who is completely thick and/or slow. They find it hard to understand normal people's conversations and jokes. Basically, they are retards. Often used in secondary schools across the UK.
I think my brother has James Syndrome
by Jinab July 31, 2006
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The mindstate of being in a stupor mode. Or in simplier form, a mindstate of slowness where the brain literally slows down for x amount of time. This mind state is extremely dangerous and people suffering from this kind of syndrome....well it's too late for them now.
When you "IM" a person, and said person doesn't reply or respond to you it means he/she has the James Syndrome. If that's the case you should inform them and tell them to seek professinal help.
by blah May 18, 2004
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when ur croych is on fire and u look like ronald mcdonald
my brother has james syndrome
by fuck james February 10, 2005
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when faced with a serious task or job to alleviate or get pressure off your self fake an injury or ailment
To get out of cutting the grass today I said I hurt my back.
To get rid of pressure Lebron James said his elbow hurt, ie; Lebron James Syndrome
by Big_Cat34 May 16, 2010
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Alex James Syndrome: occurs once select patient is put in social circle he/she is comfortable with and transforms into a massive egoist/ cheese enthusiast
"Wow he's cocky"

"I know must be Alex James Syndrome"
by BlurCunt July 2, 2017
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When a man (generally a W.A.S.P.) has a sexual preference to one or more different race over that of his own.

In the James Bond films, James sleeps with women of all ethnicities. He doesn't often court British women, as shown by the way he treats Money Penny.
"Hey man, why don't you go out with Patty?"

"I'm not really attracted to Irish girls, I've got James Bond Syndrome."
by Another Todd C. from NJ July 22, 2008
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Singing "You're Beautiful" quietly in an ear in order to score with a girl.
"Dude, How did Partario score?"
"He's got James Blunt Syndrome"
by Thegreatnick April 5, 2006
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