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This word was first borne with Unreal Tournament. One of the powerups that this game has includes a Shock Rifle that kills the enemy with one shot, no matter where it's hit. To Istagib, basically, means to kill with one single blow your opponent. Eventually used in Online Games.
Don't aggro those mobs, they'll istagib u since u r lv 5 and they're lv 14.
by Kenjitheninja December 12, 2006
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