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1.
Controversial French flick released in 2002, directed by Gaspar Noe. Won the "Bronze Horse" award at the Stockholm Film Festival and was nominated for the Palme d'Or at Cannes. Also one of the most difficult movies to watch, due to a 9-minute rape scene and a guy getting his face caved in with a fire-extinguisher to some really creepy-ass music.

More than 200 people walked out of Irreversible at Cannes, mostly due to its lengthy rape scene.
by Brian Chidueme October 02, 2007
 
2.
Something of which, once it has occured, cannot be changed nor undone.
Person 1: I just burnt my old diary!
Person 2: Are you sure you did the right thing? It's irreversible, you know...
by Dina June 14, 2006
 
3.
losing your virginity...cause you can cry but you wont hide!!!
that just counts for girlies...
for dudes, the fact that you are/will be a father, but in this case you can run and hide...

unfair
-hey, where Marcos Jr. marcos? how s he doign in the kindergarten...?
-last time i saw him his mother was a virgin!!!
-mmm...what a shame...aint that irreversible
by czMarcos February 01, 2008