look up any word, like darude - sandstorm:
 
1.
A quick-witted response used by a logical person in an attempt to update a nit-wit on the reality of life.
Used when the nit-wit chooses a fantasy version on what's really going on. The quick-witted person would respond with the truth, then back it up by saying "In Real Life"

"You ain't the queen dishwasher. In real life."
by Once Again March 17, 2013
 
2.
the top level of seriousness, to be too serious,
In real life did u jus do dat dumb shit?
I cant believe she jus tried to play me, like in real life..
by Licia9008 August 14, 2008
 
3.
A show with teens 12-14 years old who compete in real life experiences.
This show is in its 3rd season.
"OMG In Real Life is on!"
"It's an ok show, dude."
by A380101 November 04, 2011