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5. ISU
Also known as Illinois State University and also commonly known as "I Screwed Up" because upon the rejection letter to University of Illinois-Urbana Champaign(UIUC), the individual realizes that he/she did in fact screw up in high school and also screwed up the rest of their entire lives because they will now be obliged to attend a far less impressive, selective, and inferior University and will spend the next 4-7 years trying to graduate in order to obtain an average degree.
Kid: "Mom, I got rejected from UIUC..."

Mom: "So what's that mean?"

Kid: "Looks like I'm gonna havta go to ISU"

Mom: "You really screwed up, didn't you?"

Kid: "I sure did..."
1. ISU
Iowa State University, a school located in Ames, Iowa.
ISU's mascot is the Cyclone.
by Isi Oamen Jun 28, 2004 add a video
2. ISU
When referring to colleges, a joke is commonly made using the acronym ISU, meaning "I Screwed Up"
Mark could have done so much better, but instead he went to ISU.
3. ISU
independent study unit , for school purposes
Man did u start your ISU, it's worth 15% of your mark and it's due tomorrow!
4. isu
Idaho State University. The Bengals.
ISU's ________ team sucks this year like they do every year.
by addicted Mar 1, 2005 add a video
6. ISU
Illinois State University in Bloomington-Normal Illinois.
ISU are the Redbirds.
by Redbirds rock Sep 27, 2004 add a video
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