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4.
A popular phrase coined by radio DJ and tv personality, Wendy Williams. How You Doin?! is not only a greeting of the show, but when something or someone is very gay.
Jordan *Very feminine and flamboyant*: Hey miss honey, what's goin on sweetness?!

Kalisha: How you doin?!?!
by Tyrell Jenkins October 14, 2006
 
1.
Pick up line originated from the character "Joey" on the famous NYC based TV show "Friends"
"Hey, how YOU doin'......"
by AK March 14, 2003
 
2.
Pick-up line that never fails unless it's truely responded to.
Guy #1 "How YOU doin'?"
Girl #1 "tehe!"

Guy #2 "How YOU doin'?"
Girl #2 "I'm alright."
Guy #2 "What?..... Dear GOD!!"
by ellipsisO December 10, 2003
 
3.
A quite funny pick-up line often used by joey from friends when he sees a women he likes.
A hot women walks past Joey
Joey: *sees a women he likes* walks up to her 'How you doin?"
by HabDan January 03, 2009
 
5.
(exp.) 1. A phrase, originating in New York, used as a combination greeting, response to itself, question of welfare, response to FOGEDDABODDIT!, and response to YOU TALKIN' TA ME?.
"'ey. How YOU doin'?" "How YOU doin'?" "FOGEDDABODDIT!"
by Razukin December 01, 2002
 
6.
an extremely annoying way that desperate guys, thinking they are cool, will greet a pretty girl on the streets. (usually accompanied by the old up and down and a head nod to his boiz) After this comment is issued, said individual will stare blatently at the girls butt/boobs.
Super Fiine Girl: (looks at the guy and looks away fast)

Creeper: Hey shawty, how you doin'? (eyes on boobs)

Super Fiine Girl: Go fuck yourself.
by superfinegirl September 06, 2008
 
7.
official greeting of the Wendy Williams Show
im fellin sexy how you doin'?
by sdf189 October 02, 2009