The inability to get laid.
Condoleezza Rice is so horizontally challenged, it's not funny.
by Assweepay September 23, 2005
2 more definitions
An overweight person.
I'm sick of being horizontally challenged, it's time to get a gym membership around here!
by Mr Natural June 07, 2007
A large fat fuck that is literally challenged to walk. He usually wobbles as he creates massive earthquakes upon his massive kankles. Usually a horizontally challenged person whether it be a guy or girl smells like shit because they do not wash under their rolls or titties.
Rosie O'donnell is horizontally challenged.
by MrBlik October 30, 2009