Top Definition
(pronounced Hah-Pop-Yoo-Bray-Nee)
The ever elusive holy grail of dating: the hot, popular, brainy girl.

It's common to find someone with 2 out of 3, but rarely all 3.
"She's hot, popular and brainy! She's hopopubrainy!"
by Fungusmonkey September 18, 2008
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