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1.
Homozygous: having two of the same alleles for the specific gene, opposite of heterozygous...

Quite possibly the coolest word on the planet
That Hamster is Homozygous Dominant
by Cliet May 13, 2005
 
2.
a play on words to describe something as "gay".
John: I'm going to go throw rocks at a lake for a few hours while gazing into the sunset.

Jack: that's homozygous but okay.
by julpeasuarez March 01, 2010