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43.
Derived from a slice of mothers home baked cake, something that is the best. Gone on to be used to mean 'best friend' or 'buddy'. Often used after the word 'nice'
instead of 'thanks buddy' 'nice, home slice'
by Tom2409 January 27, 2008
 
44.
a white bitch wanta be a black nigga...since tha nigga say homie tha white bitch say homelsice
me and my homeslice is goin to the mall today
by brownsugar12 May 22, 2005
 
45.
A convenient vag...In other words, an easy piece of ass waiting at home.
My housewife is a perfect Home Slice.
by Urban Brat III March 27, 2009
 
46.
An icecream eating, underpants wearing, cookie-cutting home-body. Normally residing in suburban six packs. Sometimes referred to in Australian terms as a Jason
"you commin out tonite home slice?"
"na can't tonite... i have to vacuum my tilled floor"

by Mick the Mouth May 26, 2008
 
47.
A deragotory term for a friend/stranger whom is annoying or a poser.
Check out home slice over there rockin' the mullet!
by Rusty26 January 12, 2006
 
48.
For Immigrants, a fleeting glance of how things are back home.
The Indian student read the newspapers - hoping to get some home slice, and feel warm over it.
by ManasM May 05, 2006
 
49.
a cool street name like poop dawg, pee diddle, or gary
yo home slice,what up
by josif hasmr October 04, 2003