A word often used by little white kids who are trying to be cool. Also is an out of date term used to describe a friend; recently replaced by homie(still not cool for white kids to say)
Kyle: I'll see ya later.

Tyler: WHOA, hold it homeslice, you left your keys.

Kyle: WHO SAYS THAT! and thanks.
by IscZner June 22, 2008
A good friend, aka a homie. This word is used when either greeting or departing from your homie. For example, "Yo homie, what's up!" Likewise, "Alright homie, I gotta dip like a potato chip." This term can also be used when asking your homie a question or making a bold statement (i.e.) "Hey homeslice, how much cheddah do I owe you?" or "Homeslice, you trying to rip me off yo?"
A good way to remember this term is to conceptualize a pizza pie. Assume every piece of pizza is a friend. You like slices of pizzas in the same respect you like your homeslices.

In essence,

Pizza slices = homeslices = homies
by Miss. Wiz March 21, 2010
A very close friend whom you have known for a long time.
"I love my homeslices! We've known eachother

since pre-k!"
by I am your mom's mum. June 04, 2009
A person you could trust with anything/love in a platonic way; one with whom you roll deep.
Person 1: Oh my God I hate that girl!
Person 2: Don't you dare say that, she's my homeslice.
by SS21 March 03, 2014
1. A slice of homey-ness

2.A friend/amigo. One who you are "tight" with
1. Murphy : Mildred, why did we throw out that old sofa?
Mildred : Because it was old dear...
Murphy : But it was a homeslice!

2. Wannabe G 1: YO YO! What up G-dog?
Wannabe G 2: Aww nuthin homeslice, jus chillin...
by 13Pheeble November 09, 2008
A friend or buddy. Synonym for dude or homie.
Me: What's up Homeslice?
Friend:Oh nothin'. How 'bout you?
by Twinkie Bottlepop November 12, 2012
Friend or buddy
Kurk is my home slice.
by Definitelytevs October 04, 2015

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