A good friend, aka a homie. This word is used when either greeting or departing from your homie. For example, "Yo homie, what's up!" Likewise, "Alright homie, I gotta dip like a potato chip." This term can also be used when asking your homie a question or making a bold statement (i.e.) "Hey homeslice, how much cheddah do I owe you?" or "Homeslice, you trying to rip me off yo?"
A good way to remember this term is to conceptualize a pizza pie. Assume every piece of pizza is a friend. You like slices of pizzas in the same respect you like your homeslices.

In essence,

Pizza slices = homeslices = homies
by Miss. Wiz March 21, 2010
To be used in same context of of Homeboy.
person 1:"Yo my homeslice, holla up in yo face!"
person 2:"Indeed."
by Bish November 24, 2003
synonomous to "homie".
def 1: means good friend or buddy
def 2: means someone who seems like a little slice of home, thus home slice
Hey whassup home slice.
by Jay C October 16, 2003
a friend or buddy
'sup my homeslice? harvard jv field hockey is da bomb...'
by the shiznit March 07, 2003
Friend, buddy, pal
Me 'n my homeslice are going to chill down at the mall today.
by Anonymous May 29, 2002
One who is close to you
"That's my home-slice from P town"
by Tek Fresh February 23, 2003
synonomous to "homie".
def 1: means good friend or buddy
def 2: means someone who seems like a little slice of home, thus home slice
Hey Shan (aka Home Slice)
by home slice February 28, 2005
A complimentary term of endearment often used when sending well wishes.
Goodnight homeslice, I hope you have pleasant dreams.
by N April 08, 2005

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