To condemn as a failure; used as an expletive to express anger, annoyance, disgust, etc.
A women walks out of a store, carrying paper sacks, it is pouring rain outside, much to her dismay, the bottom of the bags break open, and she promptly states "Hoisington"!
Hoisington, home of the Cardinals, otherwise known as Ho-town, is where most teenage boys from the Great Bend area go if they want a garuantee to get laid. The town is known for its enormous array of sluts who will blow any guy who comes wandering into the city limits. Girls there are also quite dramatic and try to cause as much drama as humanly possible. Furthermore, you are likely to catch an STD, so please do not choose Hoisington unless it is a last resort.
"Dude I needa get laid"
"Problem solved, Hoisington has plenty of chicks who put out."
Hell ya dude, we better buy some rubbers and wrap that shit twice so we dont catch tha herps!"