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1.
A pretty good show on Cartoon Network with an interesting sense of style, colorful animation, and unusual, often absurd comedic situations. The show often utilizes morphing scene transitions, sentences spoken in Japanese language, and loud background music that comes from the titular band. Yes, the three main characters: Ami, Yumi and the band manager Caz are all based on real people. One of it's problems is that the secondary characters sometimes share a similar look, use the same wierd gestures, and some are just too one dimensional, grotesque, and unmemorable. Some people feel that the animation is derivative to Japanese anime, while making a mockery of the style. This is disputable, as the show's style is built upon Japanese culture, but it's drawn entirely in an American studio that uses it's own animation style.
"I kinda think Hi Hi Puffy AmiYumi is good. It's genuinely original, playful and wacky, and I just love the main characters. It sure has flaws, but I can forgive them as they don't annoy me too much. I'm not a critic, I'm just having fun, and some of the maverick animation in this is stimulating, while the comedy is often so ridiculous you just have to laught and enjoy it."
by BKMorris October 16, 2006
 
2.
it's like a show with to rock stars who are japanese and bad stuff is always happening to them and the animation is really crappy and the story line kinda sucks but then it's made for like little kids who will watch anything.
me: hey have you seen that one show on cartoon network?
chibi-san: what's it called?
me: hi hi puffy amiyumi.
chibi-san: yup it's really retarded.
me: yeah.... hey want to watch Fullmetal Alchemist?
chibbi-san: yeah that sounds cool
by mizu June 20, 2006