Top Definition
(Her-pe-siffi-gen-a-lie-tus) Noun: a term used to describe having more than one STD (Sexually Transmittable Disease). Typically used when describing a person who is known to sleep around with other persons who may have an STD.
She is such a skank, she's probably got herpesiphigenilitus!!

Sure he's hot, but you know he's got herpesiphigenilitus right?
by Charles McLoughlin April 13, 2008
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