Top Definition
A phenomenon common to TV sitcoms and commercials, but occasionally occuring in real life wherein an overweight or otherwise unattractive male seems to have obtained a mate of much greater attractivesness. The syndrome is named for the character "Doug Heffernan" from the TV series "King of Queens", but is also visible in other shows such as "Seinfeld" and "(most especially) "The Drew Carey Show".
Did you see that couple? It was a classic case of Heffernan Syndrome!

also acceptable:

That dude is such a Heffernan; she's too good for him!
by Michael Patrick February 15, 2006
9 Words related to Heffernan Syndrome

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