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3.
Someone attempting to speak to one another while listening to ear bleedingly loud music through their headphones.
Guy 1: Hey dude did you hear about Katie?
Guy 2: WHAT?!?
Guy 1: Are you retarded?
Guy 2: YEAH!. (turns off music) I'm sorry what?
Guy 1: Damn, must be headphone syndrome.
by brandonXcore April 01, 2007
 
1.
When someone is wearing headphones and speaks very loud because s/he tries to speak over the music.
Mike: Hey man how's it going?
Joe:I'M FINE, WHAT'S UP WITH YOU!!!!!?
Mike: Whoh man, watch it you're suffering from a little bit of headphone syndrome
by Black Majik September 15, 2005
 
2.
When someone has thier headphones on and they are too friggin loud they have to yell to talk
1: Hey do you wanna go to the movies?

2:WHAT?

1. I said do you want to go to the movies?

2. I'M SORRY I CAN'T HEAR YOU WHAT?

1. Forget it man, you have a bad case of Headphone Syndrome
by DizzyLizzy March 06, 2007