Top Definition
A derivation of "ham-fisted," an adjective meaning "clumsy," "heavy-handed," or "indelicate."

1. To thoroughly dominate, humiliate, or destroy. See example #1.

2. A literal "hamfist." When one wraps his own fist in ham. Fisting a human with a hamfist is optional but the implication is always there.
1. "Wow, the Patriots hamfisted the entire NFL until they lost to the Giants."

"Sit down and pick up a controller. Are you ready to get hamfisted?"
by RR & TO, Linguistic Innovators February 25, 2008

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