Top Definition
The point in a House M.D. episode where Dr. Gregory House solves the puzzle and finds the one missing piece that saves the patient's life. It usually occurs the minute a patient is about to die, resulting in House bursting into the room, making an incision, pull out a live animal (sometimes), and curing the patient of their affliction.

This was named for the Pilot episode and episode 314 (Insensitive) in which a ham sandwich provoked the moment.
House Fan 1: "Why does he keep looking at the hair behind her ear?"

House Fan 2: "Oh, this is it! The ham sandwich moment!"

House Fan 1: "Look at that, the cheap hair color solution she used had chemicals that mimicked hormones, which caused her to be sick."
by Oreopie January 20, 2009
5 Words related to Ham sandwich moment

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