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1.
Hammer-ons and Pull-offs. The term is originally created by Guitar Hero fans and is now applicable to Rock Band as well.
The HOPOs in Guitar Hero 3 are a little ridiculous.
by tracyface February 10, 2008
 
2.
Slang for the City of Houghton police Department
I got busted coming back from that party for drunk in public by the ho po
by TechEngineer89 November 29, 2007
 
3.
n. (pronounced with long o, accent on 2nd syllable) slang for hospital.

Used in dialogue, text, and online status notes mostly by full-time patients, or less frequently, other hospital staff with the exception of doctors and administration.

also written as: ho'po, ho-po, or , ho'po'
When am I gonna finally get out of this filthy hopo?!
by NeuroWriter January 08, 2011
 
4.
basically any one that acts like or is a cheerleader/prep

oh and this is an original, i made it up one day
those girls are ho's , those girls are to popular for there own good

ho's, popular

ho-po
by Pinktroll October 27, 2009
 
5.
Horse porn, usually in great quantity.
Dude 1: Bro, what are you watching?
Dude 2: Just some Hopo HD.
Dude 1: GTFO my room.
by Sir Humps-a-lot May 31, 2011
 
6.
1. shortened term for holicker policker. A person who practices oral sex with either gender, regardless of gender.
a. ho - to hole lick (female)
b. po - to pole lick (male)

see definition for holicker policker
1. I am an equal opportunity lover, call me a "hopo."

by jenna lynn thome October 05, 2005