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1.
Hammer-ons and Pull-offs. The term is originally created by Guitar Hero fans and is now applicable to Rock Band as well.
The HOPOs in Guitar Hero 3 are a little ridiculous.
by tracyface February 10, 2008
8 1
 
2.
n. (pronounced with long o, accent on 2nd syllable) slang for hospital.

Used in dialogue, text, and online status notes mostly by full-time patients, or less frequently, other hospital staff with the exception of doctors and administration.

also written as: ho'po, ho-po, or , ho'po'
When am I gonna finally get out of this filthy hopo?!
by NeuroWriter January 08, 2011
3 5
 
3.
Slang for the City of Houghton police Department
I got busted coming back from that party for drunk in public by the ho po
by TechEngineer89 November 29, 2007
0 2
 
4.
basically any one that acts like or is a cheerleader/prep

oh and this is an original, i made it up one day
those girls are ho's , those girls are to popular for there own good

ho's, popular

ho-po
by Pinktroll October 27, 2009
2 7
 
5.
Horse porn, usually in great quantity.
Dude 1: Bro, what are you watching?
Dude 2: Just some Hopo HD.
Dude 1: GTFO my room.
by Sir Humps-a-lot May 31, 2011
1 9
 
6.
1. shortened term for holicker policker. A person who practices oral sex with either gender, regardless of gender.
a. ho - to hole lick (female)
b. po - to pole lick (male)

see definition for holicker policker
1. I am an equal opportunity lover, call me a "hopo."

by jenna lynn thome October 05, 2005
6 21