High Fructose Corn Syrup - a sugar substitute often used in soft drinks, candy bars, and other sweetened food products.
One of the ingredients in Dave's cola was HFCS.
by Wiseman July 10, 2006
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1. HFCS is a refined sweetener made of corn. It causes a nerve ending in your brain to not detect when your stomach is full, which will lead to overeating. It also has a 1/3 chance of containing mercury.

2. HFCS, Dude!!!!
by Shareeb4Prez May 7, 2009
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damn that guy is such an hfc! id love for him to be my boyfriend!
by schlirshman September 12, 2010
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Acronym for "Holy Fucking Cheese" used to convey amazement, disgust, excitement, and many other emotions
HFC that coat cost 10000? Or HFC I won the lottery!
by Llam26 August 28, 2018
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Holy Freaking Crap. Used when any extreme moments happen.
John: Dude, I heard that Kenny hooked up with Mrs. Brown, the middle-aged lady that's always running around the block.
Tom: HFC!

Taylor: Stacy is such a whore! She's slept with all 17 of my ex-boyfriends!
Jane: HFC!
by Garry With Two R's January 28, 2010
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The HFC stands for Holway Fighting Crew. This bunch of 'ard nuts go around the streets of Taunton trying to steal people's wallets or just trying to 'smack' as many people as possible. Despite these ways of intimidation all they've really done is thieve from the local corner shop and spray their HFC tag on walls around the area. So if you are visiting Taunton look out for white tracksuits and burberry hats, because they're well good innit.
'hey mate look, a greeb, let's get the HFC to bully him into giving us his wallet.
by swarkin July 9, 2006
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