Top Definition
A very contagious virus due to being a soft ass motherfucker, caused by acts of softness
Chris: Yo Tyler, how are you drunk already, thats only your second beer!?
Tyler: Yo man chill!
Shaun: He has H1SOFT1, uh-oh
Devin: HAHAHAHAHA!
by Munsen91 July 20, 2009

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