when you wake up in the morning and you hate your life... that is H.M.L.S. Or hate my life syndrome as it is also known.
it is also possible for certain individuals to contract this horrible condition during the middle of the day.
Take Durdey for example, constant H.M.L.S. =]
*wakes up in the morning* "argh! H.M.L.S!"
"hate my life!"