so serious and positive that you are H.I.V. positive
guy 1: dude are you sure we should be doing this?
guy 2: im H.I.V. positive that we should
more acceptable to say if you actually have AIDS
from a South Park episode
"are you sure dude?" "yeah man, I'm HIV positive"
This is a way of determining whether or not your friend is completely and totally sure of themselves when they are explaining something to you. Please see the examples for further explanation.
"Hey Tommy whats going on?"
"Jimmy I've got some bad news... The pigs went through our lockers today and found Adam's crack"
"Tommy.. Are you positive??"
"Are you HIV POSITIVE?"