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1.
Having sex with your partner after being yelled at for not having sex with your partner.
So after I let her cool off I went up and guilt fucked the hell out of her the way she wanted. It was all good after that.

She was like, "Don't be all trying to guilt fuck me."

"GOD Damn, I hope that wasn't a guilt fuck."
by Brother Sunday May 25, 2012
 
2.
To have sex with someone (whom you presumably dislike) with the intention of calling them in 3 months claiming to have contracted a minor STD.

This may be generally considered a passive aggressive version of the ever popular Hate Fuck.
Man, I totally just guilt fucked my ex. I hope she buys that she gave me the herp.
by ghost_brigade February 08, 2009