Top Definition
Grissues : 'girl issues'.

Any female problem/s usually arising as a result of PMS, sickness, bitchiness or drunkeness.

It should be noted that grissues can often be used as a false excuse when somebody is trying to get themselves out of a situation.
John: Dude where did you n Joanne disappear to at the party last night?
Mike: Grissues!
John: Say no more...
by supanover_ek_sez June 28, 2010

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