Top Definition
The bone type structure inside a girl's vagina that you must maneuver around to get to the "g-spot" while fingering her.
Girl: "Pleasure me more baby!"

Guy: "Okay I must get past the Great Wall Of Vagina"
by DWEAVE AND DIRTY January 22, 2010
A female version of "Cock Blocking". If a girl is out with a guy or girl and prevents them from getting lucky due to something they do, or just by being there.
Dave - Why am i having no luck tonight with girls tonight?!?!?

Tracey - Oh, that might be my fault, inadvertent Great wall of Vagina. All the girls must think you're with me.

Dave - Well fuck off then! I want to get lucky!
by Sir Dave Longpipe I January 10, 2014

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