To be inadvertently screwed/fucked/hosed by a person, business, corporation or computer algorithm.
"Man, when you called in sick yesterday the supervisor changed my shift to cover yours and then I had to cancel my date with that hottie I met at the party last weekend. You really goat fucked me."
"Brad had told all his friends to click on the Google ads on his webpage so he could get more money. Too bad his friends didn't actually buy anything; the Google algorithm kicked him out of the program and now he doesn't get paid at all!"