A a worldwide, independent defense agency, civilian-run by exactly one-thousand and one agents of varying skills and expertise (detectives, mechanics, assasins, pilots, etc). Lead by the enigmatic Miranda Zero and the supercomputer-of-a-babe and central dispatcher Aleph, they're called into action to clean up all the world-threatening junk that the government run organizations are typically unable to handle.
All the black projects, the mad science, the chilly encounters with the unknown, the Cold War traps... they're all sitting there like landmines. Eventually someone will trip over one of them. Global Frequency are there to catch them when they fall, and defuse the mines before they explode into mainstream consciousness and cause more pain and horror than they already have...
Are you on the Global Frequency?