Top Definition
A horrible disease where you become completely negative towards everything. Often the only words you will say are no, naw, no way, or never.
Guy 1: Dude jake is so grumpy its like he has a stick up his ass.

Guy 2: yeah he has Glazesyndrome he's gonna be like that for awhile.

Guy 1: Fuck dude!
by Gentalmensmiley June 19, 2011
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