Top Definition
A giant, pushy, stuffy woman, typically with an abnormally large ass, cotton pants, and a pushy attitude, who consumes (at times in mass quantities) the "Toscano" sandwich from the local Italian deli (which contains provolone cheese and spicy Italian sausage).
One can only assume that they also have a large turning radius, hence the "giant".
"That Giant Toscano Eating Bitch is back again!!"

or

"Most home ec teachers seem to look like Giant Toscano Eating Bitches."
by Jenburger December 07, 2007

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