To experience sexual release; to have an orgasm. Primarily referring to women but can also apply to men.
During sexual relations, the partner might say, "Come on baby, get the poison out."
by Bill R April 19, 2010
1 more definition
When a girl is having an intense orgasm she is told to "Get The Poison Out"
During the April 8,2010 ride of Raven Alexis on the Sybian in the Howard Stern Studios the phrase was uttered. Dave Lampert Creator of the Sybian told Raven 'Get the poison out of your system Raven'. This creepy yet memorable moment is still in play as a favorite Stern sound bite.
by Orgasm Girl May 07, 2010