Top Definition
A self-inflicted developmental disabilty of millenials, caused by chronic digital media addiction, and characterized by short attention span, quick frustration, indiscipline, fatigue, and inability to absorb verbal information.
Doctor: I'm diagnosing you with game brain, probably caused by 2,000 hours of World of Warcraft, and exacerbated by 1,000 hours of GTA. I'm writing you a prescription for methadone. With treatment, you may one day be a person again.
by a j a x March 15, 2017

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the act of receiving a blow job while playing X-Box 360 or PS3
Dude, my girlfriend gave me game brain while i pwned in COD4.
by The Unknown Pseudonym May 11, 2009

The Urban Dictionary Mug

Lotsa space for your liquids.

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The Urban Dictionary Mug

Lotsa space for your liquids.

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The Urban Dictionary Mug

Your favorite word on a white mug.

Create a mug

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug

The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

Buy the t-shirt

The Urban Dictionary T-Shirt

Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).

Buy the t-shirt