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1.
A large cut out line of a snortable chemical substance, usually illegal.
The gacker is characterized by the strong and immediate physical/vocal response of the individual who snorts the gacker.
Oh man, I just took a huge gacker!

That gacker gave me a phat drip!
by Jamison March 14, 2005
 
2.
Gacker (n): Someone who plays the game of genetics using both zinc fingers and stem cells.
John, the gacker, did the devil's work juggling them stem cells.
by forkrul assail June 11, 2010
 
3.
A person who uses crystalmeth by slaming it in there veins.
Foxi is a gacker. tom said Foxi and cyndi was all gacked out.
by foxiknew September 12, 2006