1. Can stand for get fucked and die. Used when telling someone off, insulting another and showing hatred for them, etc.
2. Can also be used, on a more happier note, to say get freaky and dance
1. pLaYa1236969: heyy bitch wanna fuck/1@?#!??
2. Guy: Wanna get on the dance floor?
Girl: Hells yeah! Let's GF&D!
abbreviation for "get fucked and die".
someone is really unkind, mean or vicious, you end all further contact by saying or writing "GF&D!"