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1. G.I.R.L.
Guy In Real Life. Guys in MMORPGs that make their character a girl. They often make other boys their boyfriend and thus, a gold digger. Then, he leaves the "boyfriend" broken-hearted and moves on to the next boy.
Somebody1:"Ugh.....why did my gf break up with me?"

Somebody2:"Maybe she was a G.I.R.L."

Somebody1:"You mean she might've been a guy?"

Somebody2:"Yep."

Somebody1:"....I'm having a headache IRL right now..."
2. g.i.r.l.
Generally known as G.I.R.L. is often used in online games when a male plays as a female online. Mainly used to flirt themselves into a male online player's bank. Meaning they will ask for items or money in-game and will most likely get a yes just because of their "female charm".

Can also be used aside from online games. ie, chatting, profiles, social networks. etc.

G = Guy(s)
I = In
R = Real
L = Life
Guy1: Are you a g.i.r.l. too?
Guy2: Always have been.
3. G.I.R.L.
Guy In Real Life. Guys in MMORPGs that make their character a girl. They often make other boys their boyfriend and thus, a gold digger. Then, he leaves the "boyfriend" broken-hearted and moves on to the next boy.
Somebody1:"Ugh.....why did my gf break up with me?"

Somebody2:"Maybe she was a G.I.R.L."

Somebody1:"You mean she might've been a guy?"

Somebody2:"Yep."

Somebody1:"....I'm having a headache IRL right now..."
4. G.I.R.L.
Girl In Real Life. A self explanatory chatroom term.
<sxy_grrl_69> hi asl
<clued> don't talk to him. he's a G.I.R.L.