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1.
Fufe is another word for dude. It was first originated by beach-goers in FL, but soon spread like wildfire around the globe. It can be used to describe males or females, but it may only be used on really nice, cool people. Fufe can be modified to your liking by adding an "N" to the end meaning "Very cool". Or you can say Fufe-a-licious meaning "extremely cool".
"What's up fufe?"
"This new Phantom Planet cd is fufen!"
"Your outfit is fufe-a-licious!"
by Sweet Lou and HBG November 12, 2003
 
2.
Originated early 2011;

The word 'Fufe' is mainly directed at males. A 'Fufe' is a camp guy, Not necessarily gay, borderline, but straight.

Fufe can be replaced with gay, I.E. You're such a Fufe!

You can add a Y to the end of the word to get a different sense of Fufe.
Steve you look like such a Fufe!
Steve you're looking very Fufey today.

You're gay!

No I'm not, I'm a Fufe.
by moojuice122345 March 14, 2011
 
3.
Fufe can also mean friend or friends. (Add an "S" for more than one person/animal/thing you chose as your friend)
"Don't mess with her, she's my fufe."
"Shout outs to all of my fufes!
by Sweet Lou and HBG November 15, 2003