1. extremely tired, too exhausted to engage in sexual acts of any kind, to tired to shag
2. drunk to the extreme
fuckered exhausted knackered shattered wasted pissed
Adam was so fucknackered after a long hard day that he didn't even try to get a leg over his missus and fell asleep as soon as his head hit the pillow.
I was so fucknackered after drinking that second bottle of wine I passed out and rolled off the bed.