Either a literal hole for fucking, such as a pussy, or a derogative term implying that a person is giant waste of flesh, at best a life-support system for their fuckhole.

See: alcove, bat cave, bear trap, bearded clam, bearded taco, beaver, bermuda triangle, box, bucket seat, cake, chuff box, cockpit, cooch, coochie, coochie-pop, coose, cooter, cooze, crack, crawl space, cum depository, cum dumpster, cuntcake, cunt, cunny, donut, dripping delta, felted mound, fillet-o-fish, finger hut, fish, fish taco, front bum, fly catcher, fuckhole, garage, gash, gates of Heaven, golden doorway, Grand Canyon, growler, hair pie, hatchet wound, heaven's door, hole, honey cave, honey pot, hot box, jaws of Hell, lobster pot, loins, loose meat sandwich, lotus, love box, love canal, lower lips, meat wallet, muff, nooch, nook, nookie, parking spot, peach, pearly panty gates, pocket, poon, poontang, purse, pussy, quiff, quim, rat trap, scratch, sheath, slash, slit, snapper, snatch, space, split, stench trench, tampon socket, temple, thingy, tool shed, tuna, tunnel, twat, undercut, vagina, vertical smile, wishing well, whisker box, womb, x, yoni

a hole used for fucking

a hole that is dug in the ground used for fucking on lonely nights

An thoroughly unpleasant location with highly negative connotations for the speaker.

Nothing other then a Pussy, or an asshole.

vagina

Noun: 1. Any orifice into which a penis can be inserted. (e.g. mouth, vagina, anus). 2. A person who is willing and able to have the penises of multiple men into his or her anus, mouth, and vagina.