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1.
1. Used to tell a person to "shut the fuck up" and call them a bitch in simple three word phrase. This use of the word commonly includes the use of the middle finger.

2. Also used to end a conversation or when parting ways. Can be replaced with "goodbye" "see ya later" and "hasta la viesta, baby."
1. "Graham, you need to do your homework right now!"

"hey mom, guess what. Fuck up, Bitch" *flips off mom*

2. "Hey man, thanks for the ride."

"Oh it was no problem dude."

"Alright, well I'll see you later."

"Yep. Fuck up, bitch."
by just a nigga who loves titties April 21, 2010