Top Definition
A fairly new alcoholic drink popular amongst the hipsters. Known for its taste which most find disgusting, but a select few simply can't resist.

Made by mixing 1.5 shots of Jack Daniel's Tennessee whisky, 1.5 shots of Grey Goose Vodka, and 1.5 shots of orange juice.
Guy: Bartender, get me a Frank-O-Frank.
Bartender: A what?
Guy: What, you've never heard of it?
by crazymothereffinhipster April 25, 2010

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