A reference to a Shadow Priest spell from the game "World of Warcraft" known as Mind Flay. It is used as a "filler" answer for any question, as a term of comradery, or as a social greeting.

Tyflayz/Typhlayz is a variation of the word referencing the Druid Moonkin spell Typhoon which is mega-lulzy.

It should be noted that this term originated on the Baelgun server of World of Warcraft, and was repeated many thousands of times by rampant homosexual deviant Pointyears and well-known attention-whore boob-flasher Viviana.