Top Definition
Illness contracted by Flagstaff women that causes extreme disproportion between the upper and lower body. Usually subjects are depicted with a normal-ish upper body and the unfortunate swelling and inflation of buttocks and thighs. It is believed too be a natural phenomenon caused by the high elevation and cold weather of Flagstaff, causing over preparation of the body in storing lower body fat for the cold of the winter season. DNA specimens suggest these subjects are close relatives with the hippopotamus.
I thought that girl was pretty hot but when she stood up I realized she had been afflicted by Flagstaff Syndrome.
by Trent Kurth February 06, 2009
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