Top Definition
Is the terminal disease of the brain in which the sufferer cannot spend a whole day without repeating word for word jokes from the previous nights Family Guy episode. This disease results in the deterioration of the brain, where the victim becomes a zombie to plagerized jokes.
Mark: "So then Stewie was all like 'What the duece!', haha."
Adam: "Mate, you might want to get your Family Guy Echo Syndrome checked out?"
by Scimitar October 25, 2007

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