Short for freeze the fuck up. You say this when you're pissed off that something you put in the freezer isn't freezing fast enough.
Joe: I really wish this beer would hurry and ftfu..
by Bringin88 August 26, 2009
Fed the fuck up. When you're half way through getting done with exams and can't take it anymore. It can also refer to being extremely bored or even just annoyed at work. People may also use FTFU in reference to someone being annoying or when you can't be bothered doing more chores.
'There's so much to learn. I'm so FTFU!'

"Work is slow today. Im FTFU and just want to go home"
by nikster January 19, 2014
Fucked the fuck up.
In reference to extreme levels of inebriation from alcohol, weed, or other drugs. Usually posted as a facebook status, sent as a text message, or exclaimed as 'FUCKED THE FUCK UP'

The origin of the term seems to be as a variation of the popular STFU.
FB: Nat G is FTFUUU

Text: im soo ftfu sadf

Exclaimed: THIS SHOTS FOR YOU! I'M FUCKED THE FUCK UP!
by 508WeekendWarrior May 01, 2010
Fuck That, Fuck You.
A response to an unreasonable request.
“It's your turn to clean the cat's vomit” “FTFU”.
by doodle jonesier August 10, 2013

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